Troy Lund, M.D., Ph.D.
Associate Professor, Division of Pediatric Blood and Marrow Transplantation
"Yes, we’re saving lives. But that’s not enough. I want to improve the quality of life for these kids, and that’s where I’m focusing my energy.”
"Yes, we’re saving lives. But that’s not enough.
I want to improve the quality of life for these kids, and that’s where I’m focusing my energy.”
Dr. Lund is interested in the use of blood and marrow transplantation (BMT) primarily for patients with leukemia, lymphoma, inherited metabolic disorders, like Adrenoleukodystrophy (ALD) and Hurler syndrome. His work both in his laboratory and with his patients has created many new approaches to treatment, which will ultimately make transplant safer and more effective.
Doctor of Philosophy (PhD): University of South Florida/Moffitt Cancer Center (Cancer Biology)
Medical School: University of Minnesota
Residency: University of Minnesota (Pediatrics)
Fellowship: University of Minnesota (Hematology/Oncology and Blood and Marrow Transplantation)
Dr. Lund's research focuses improving the outcomes for all patients undergoing blood and marrow transplantation by increasing the speed at which hematopoietic stem cells reconstitute the immune system after transplant. He also works to increase our understanding the pathophysiological processes underlying inherited metabolic diseases, and one area Dr. Lund is exploring is how an autoimmune reaction may trigger the cerebral form of Adrenoleukodystrophy (cALD), the most serious form of ALD. This study represents the largest screening for immune-reactivity in cALD ever performed, and further research could help identify ALD patients with immune-reactivity prior to the onset of cALD.
A Selection of Dr. Lund’s Recent Publications & Awards
Hematopoietic Stem Cell Transplantation in the Leukodystrophies: A Systematic Review of the Literature.
Musolino PL, Lund TC, Pan J, Escolar ML, Paker AM, Duncan CN, Eichler FS. Neuropediatrics. 2014 Feb 10.
Hematopoietic stem cell transplant for lysosomal storage diseases. Lund TC. Pediatr Endocrinol Rev. 2013 Nov.
Cerebrospinal fluid matrix metalloproteinases are elevated in cerebral adrenoleukodystrophy and correlate with MRI severity and neurologic dysfunction. Thibert KA, Raymond GV, Nascene DR, Miller WP, Tolar J, Orchard PJ, Lund TC. PLoS One. 2012
Outcomes after allogeneic hematopoietic cell transplantation for childhood cerebral adrenoleukodystrophy: the largest single-institution cohort report. Miller WP, Rothman SM, Nascene D, Kivisto T, DeFor TE, Ziegler RS, Eisengart J, Leiser K, Raymond G, Lund TC, Tolar J, Orchard PJ. Blood. 2011 Aug 18.
Click here to see a complete list of Dr. Lund’s studies which have been published by academic and research journals.