Angela Smith, M.D.
Associate Professor, Division of Pediatric Blood and Marrow Transplantation
“I’m fortunate to be part of a great team and great legacy of blood and marrow transplant innovation.
My hope is to better understand both the short and long-term health implications of transplant, to improve the process and make it safer."
Dr. Smith’s clinical interests include transplant for leukemia and MDS and non-cancerous disorders, including immune deficiencies, hemoglobinopathies and histiocytic disorders. She is also focused on the prevention of acute transplant related complications, as well as studying the long-term effects of transplantation and how to improve treatment protocols to lessen these effects.
Medical School: Medical College of Wisconsin (Milwaukee)
Residency: University of Minnesota
Fellowship: University of Minnesota (Hematology/Oncology and Blood and Marrow Transplantation)
Dr. Smith is researching several aspects of transplant related complications including ovarian function preservation and delayed platelet recovery following transplant. She is also involved in research looking to identify reasons why MDS and other myeloid blood disorders sometimes run in families. She also participates in a national consortium that does research on treatment for primary immune deficiencies in children.
Unrelated donor allogeneic hematopoietic stem cell transplantation for patients with hemoglobinopathies using a reduced-intensity conditioning regimen and third-party mesenchymal stromal cells. Kharbanda S, Smith AR, Hutchinson SK, McKenna DH, Ball JB, Lamb LS Jr, Agarwal R, Weinberg KI, Wagner JE Jr. Biol Blood Marrow Transplant. 2014 Apr.
Hypomorphic Janus kinase 3 mutations result in a spectrum of immune defects, including partial maternal T-cell engraftment. Cattaneo F, Recher M, Masneri S, Baxi SN, Fiorini C, Antonelli F, Wysocki CA, Calderon JG, Eibel H, Smith AR, Bonilla FA, Tsitsikov E, Giliani S, Notarangelo LD, Pai SY. J Allergy Clin Immunol. 2013 Apr.
Improved survival over the last decade in pediatric patients requiring dialysis after hematopoietic cell transplantation. Rajpal JS, Patel N, Vogel RI, Kashtan CE, Smith AR. Biol Blood Marrow Transplant. 2013 Apr.
Early hematopoietic stem cell transplant is associated with favorable outcomes in children with MDS. Smith AR, Christiansen EC, Wagner JE, Cao Q, MacMillan ML, Stefanski HE, Trotz BA, Burke MJ, Verneris MR. Pediatr Blood Cancer. 2013 Apr.
Click here to see more of Dr. Smith’s work which has been published by academic and research journals.